A evolução da radiofrequência convencional levou a uma nova modalidade de terapia, que permite trabalhar através de dois mecanismos agindo de forma simultânea: o calor e o frio. Através da criofrequência é possível alcançar com muito mais especificidade os tecidos profundos, ocasionando conforto, eficácia e resultados em tratamentos de ponta. O aquecimento gera a lipólise do adipócito submetido à terapia acarretando o aumento do estresse metabólico e consequentemente a neocolagênese devido à ativação das proteínas de choque térmico.
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